We are looking for an experienced Scientist with interest and experience in biologics discovery to join our team. In this role, you will have direct experience in antibody characterization by surface plasmon resonance (e.g. Biacore, ProteOn), binding characterization by other approaches (e.g. Fortebio, Kinexa, flow cytometry, LigandTracer) and functional assay development (e.g. ELISA).
What you’ll be doing: Your responsibilities include, but are not limited to:
• Independently design Biacore methods including direct immobilization and capture formats to assess protein-protein interactions.
• Independently analyze and interpret Biacore data with the ability to draw own conclusions in alignment with project initiatives.
• Train and become proficient in other binding technologies to assess soluble protein-protein interactions (e.g. ProteOn, Fortebio).
• Train and become proficient in mammalian cell culture and cellular binding technologies to characterize antibody molecules binding to cells (e.g. Kinexa, LigandTracer).
• Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager.
• Provides basic data analysis to interpret own experiments – assesses whether experimental hypothesis was appropriately tested and answered.
• Present research and participate constructively in working project teams and at lab meetings.
This position will be located at the Cambridge, MA site and will not have the ability to be located remotely. This position will require 0% travel as defined by the business (domestic and/ or international).What you’ll bring to the role (required):
• MS in a scientific discipline such as biology, chemistry or pharmacology with 1+ years of relevant experience; or BS with 2+ years relevant experience. Level will commensurate with experience.
• Experience with using surface plasmon resonance (i.e. Biacore) to measure protein-protein binding interactions including antibody/antigen interactions, receptors-antigens, etc.
Desirable
• Experience with other bioassay formats, such as ELISA, to measure binding interactions, functional potencies and determine protein concentrations
Why Novartis
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what’s possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.
Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
The pay range for this position at commencement of employment is expected to be between Research Scientist: $84,000 to $126,000 a year; Senior Scientist: $92,800 to $139,200; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards, in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here:
https://talentnetwork.novartis.com/network
About the roleMillions! Novartis made a decision to pursue early discovery research internally that enable us to quickly translate the...
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