The Hirschi Lab in the Department of Cell Biology at the University of Virginia School of Medicine is seeking a Postdoctoral Researcher to investigate the role of endothelial cell cycle state in phenotypic specialization during development and in disease.
Research in the Hirschi lab currently focuses on: 1) the molecular regulation of hemogenic, arterial-venous, and lymphatic endothelial cell development, 2) cell cycle regulation of endothelial cell specification, 3) vascular regulation of stem cell niches, and 4) systems and genomic approaches to studying vascular development. Fundamental approaches in the Hirschi Lab include:
Murine models of development
Human and murine cell culture models using primary and stem cell sources
Single cell and bulk analyses using next-generation sequencing, proteomics and bioinformatics
Immunofluorescence and confocal microscopy
Flow cytometric analysis and Fluorescence Activated Cell Sorting (FACS)
Candidates with experience in these techniques are highly encouraged to apply. Training in additional techniques will be provided according to the research project directions.
Postdoctoral researchers will manage their own projects and interact with other lab members and collaborators. Additional responsibilities of the position include writing and preparing manuscripts for scientific publication; making presentations at local, national, and/or international conferences; assisting in the preparation of grant applications; and establishing new avenues of research in the laboratory. This position also includes opportunities to help mentor and teach students.
Dr. Hirschi is the founding Director of the UVA Developmental Genomics Center. The Center bridges developmental biologists with genomic and clinical translational scientists at UVA and nearby health care systems, aiming to integrate genomic technologies and next-generation sequencing datasets to determine mechanisms underlying developmental defects and disease. Dr. Hirschi is also an active member of the UVA Cardiovascular Research Center, which provides opportunity for postdoctoral support on the longstanding and highly successful NIH T32 Cardiovascular Training Grant.
Minimum Qualifications:
Education: Doctoral degree in Cell/Developmental Biology or related fields at time of hire.
Experience: Prior research experience in a relevant field as evidenced by an appropriate publication record.
Physical Demands:
This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.
To Apply:
Please apply through Workday, and search for R0041121. Internal applicants must apply through their UVA Workday profile by searching ‘Find Jobs’. Complete an application online with the following documents:
A CV/resume
A cover letter
Contact information for 3 references (name, email, phone number)
Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission.Applications that do not contain all required documents will not receive full consideration.
For additional information about the position, please contact Karen Hirschi at [email protected]. For questions about the application process, please contact Margaret Weeks, Academic Recruiter at mew7ys@virginia.edu. Before a formal offer of employment is extended, the selected candidate will undergo a background check per university policy.
For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/.
The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person’s perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.
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