Oklahoma State University Center for Health Sciences Hiring for Medicinal Chemistry Scientist – NCWR at 1111 W 17TH STREET Tulsa , Oklahoma, 74107 United States Full Time

Full Job Description

Position Details

• Req ID: req16516
• Position Title: Medicinal Chemistry Scientist – NCWR
• Position Type: Staff Full-Time
• Position Number: GS9198
• OSU Campus: Tulsa – Center for Health Sciences/OSU Medicine
• Department: Center for Wellness and Recovery
• Location Address: 1111 W 17TH STREET, Tulsa, Oklahoma, 74107, United States
• Hiring Supervisor:
• Hiring Range: (Contingent upon available funding): Commensurate with education and experience
• Work Schedule: Typically 8 hrs/day, 5 days/week
• Faculty Appt Period: Job Summary

Job Summary: THIS IS A GRANT FUNDED POSITION

The National Center for Wellness and Recovery (NCWR) is currently expanding its medicinal chemistry team with openings at all levels, ranging from mid- and entry-level positions. Preferred experience with molecule design, organic synthesis, purification, combinatorial chemistry, and spectroscopy (NMR, IR, LC/MS) are highly preferred. The most ideal candidates will have experience in heterocyclic synthesis techniques, chiral synthetic methods, and purification techniques, and will have a strong working knowledge of the supporting literature relevant to synthetic methodologies. Regardless of level, significant bench-work is expected from all candidates.

The National Center for Wellness and Recovery (NCWR) at Oklahoma State University Center for Health Sciences (OSU-CHS) was publicly launched in 2017 with a mission to inspire hope for people suffering with chronic pain and substance use disorders through treatment and research. The NCWR was the recipient of nearly $200M from Purdue Pharma as part of their settlement with Oklahoma and the funds are being leveraged to advance the science of addiction and pain. Currently, we are making multi-million-dollar investments in neuroscience research and drug discovery competencies including medicinal chemistry, molecular biology, animal models, and pharmacology. We are uniquely organized within OSU-CHS organization to allow researchers to be highly focused on the urgent mission of the NCWR as a priority. NCWR researchers and scientists are expected to seek ways to rapidly translate new mechanism-based treatment modalities to patient care. The NCWR is currently building a 30,000 square foot pharmaceutical research facility as part of a new medical campus in downtown Tulsa. The NCWR endorses a culture of teaching, learning, and collaboration, thus creating opportunities for our people to grow in their career through direct interactions on multidisciplinary teams with colleagues. This is an opportunity to join a well-funded and growing team that is focused on making a positive impact in the lives of those suffering from addiction and/or chronic pain.

Environmental Hazard: Possible exposure to hazardous material, hot and cold, blood borne pathogens. Exposure to rodents.

Physical Requirement: Ability to lift and carry 20 pounds, stoop, reach, stand, walk, finger, grasp, feel, talk, hear, see, and perform repetitive motions with or without reasonable accommodations.

Special Instructions to Applicants

Education & Experience Position Qualifications: Required:

Scientist:

• Requirements:
  • Bachelors in a field related to biochemistry, cell biology, molecular biology or related field, or equivalent experience
  • 2 years of post-Bachelors experience in academic, industrial, or related field with sustained productivity
  • Conducted and published novel results from their own research activities.

Principal Investigator:

• Requirements:
  • Ph.D. in a field related to biochemistry, cell biology, molecular biology or related field, or equivalent experience
  • 5 years of post-Ph.D. experience in academic, industrial, or related field with sustained productivity
  • Conducted and published novel results from their own research activities.

Research Investigator:

• Requirements:
  • Ph.D. in a field related to biochemistry, cell biology, molecular biology or related field, or equivalent experience
  • 2 years of post-Ph.D. experience in academic, industrial, or related field with sustained productivity

Skills, Proficiencies, and Knowledge:

• Design molecules related to drug discovery projects and develop feasible synthetic routes, purification methods and apply analytical instrumentation to prove structure and purity.
• As needed scale-up molecules to multi-gram amounts for use in animal models.
• Develop methods for chiral syntheses, separation, and analysis.
• Utilize high throughput purification systems.
• Interact within multi-disciplinary drug discovery research teams to develop structure-activity-relationships though iterative synthesis and pharmacological testing.
• Write grant proposals, present at internal meetings, plan budgets, and supply technical content to patent applications and other documents.
• Supervise staff including PhDs and non-PhDs, including goal setting, mentoring, and allocating resources.
• Be willing to learn new analytical and chemical techniques and apply them in the laboratory independently or as part of a team.
• Familiarity with chemical structure drawing software and other software related to chemical synthesis and drug-design.
• Attention to detail in record-keeping and lab safety.

Preferred:

• Experience with molecule design, organic synthesis, purification, combinatorial chemistry, and spectroscopy (NMR, IR, LC/MS) are highly preferred.
• Operational and interpretational knowledge of NMR, HPLC, LC/MS.
• Grant, publication, and report-writing experience.