University of Virginia Hiring for Senior Research Scientist, Division of Hematology and Oncology at Charlottesville, VA Full Time

The Cancer Center at the University of Virginia seeks a Senior Research Scientist to work in the laboratory of Dr. Thomas Loughran Jr. The incumbent joins an interactive group of motivated scientists to study the pathogenesis and treatment of hematologic malignancies with a focus on large granular lymphocyte (LGL) leukemia and acute myeloid leukemia (AML). Candidate will join a highly collaborative research team to investigate the pathogenic mechanisms in LGL leukemia including somatic mutations; epigenetic, biochemical and signaling alterations; and immunologic events such as antigenic drivers of cytotoxic T-cell responses. Therapeutic development efforts will include target identification, validation and rationale; in vitro testing and mechanistic studies in cell lines and primary patient samples; and in vivo efficacy trials in preclinical models to support the translational development of approve and experimental therapeutics alone and in combination regimens.

Candidate must have a PhD degree in Molecular Medicine, Molecular Biology, Cell Biology, or related.

Minimum five years of research experience to include each of the following: cell biology, molecular biology, cell signaling, immunology, drug screening, culture and genetic manipulation of primary human material and cell lines, as well as pre-clinical in vitro and in vivo experimental therapeutic development is required.

Position will provide instruction, training and mentoring to undergraduate and graduate students and technicians, therefore a minimum of one-year experience in a teaching capacity (including teaching assistant or tutor) required. Experience acquired as an undergraduate or graduate student is acceptable.

Position will require administrative and managerial duties, including but not limited to, implementing laboratory biosafety and chemical safety guidelines, completing regulatory filings for animal usage and human subjects research, managing and guiding research projects in the lab, and coordinating collaborative research projects with investigators within UVA and at other institutions.

Position will also contribute to the writing of manuscripts and grant applications, therefore demonstrated experience and success in these areas is required. ­­­Successful candidates must have effective oral and written communication skills as evidenced by a solid track record of scientific manuscripts and poster presentations.

In addition to the above responsibilities, other duties may be assigned.

The University of Virginia is located east of the Blueridge Mountains of Virginia just 30 minutes from Shenandoah National Park and 100 miles south of Washington DC. Charlottesville is often voted one of the best places to live in the US, with a vibrant arts and music scene, pristine nature, local wineries and breweries, and tons of small-town charm. Competitive salary, space, and start-up packages will be provided.

This position is located in Charlottesville, VA.

This is a restricted position; continuation is dependent on funding and satisfactory performance.

Priority review of applicants will begin April 10, 2023 and this position will remain open to applications until filled.

The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position.

To Apply:

Please apply through Workday, and search for R0045784. Internal applicants must apply through their UVA Workday profile, search “Find Jobs,” and search for requisition #R0045784. Complete an application online with the following documents:

• CV
• Cover letter
• Contact information for 3 references
• Statement of research interest

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Internal applicants must apply through their UVA Workday profile by searching ‘Find Jobs’.

For questions about the application process, please contact Jessica Russo, Recruiter, at [email protected].

The University of Virginia is an equal opportunity and affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.

For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/.

COVID Vaccination Requirement and Guidelines

Please visit the UVA COVID-19 Job Requirements and Guidelines webpage prior to applying for current information regarding vaccination requirements and guidelines for employment at UVA.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person’s perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.