SCHOOL/UNIT DESCRIPTION:
Sarafan ChEM-H is a new interdisciplinary institute focused on connecting Chemistry, Engineering, and Medicine for Human Health. The institute was founded as a joint venture of the Schools of Medicine, Engineering, and Humanities and Sciences. The proximity of world-class biologists, chemists, engineers, and clinicians at Stanford presents a unique opportunity to study human biology at a molecular level, to translate this knowledge into groundbreaking products and services that promote healthy living, and to educate a new cadre of “physician-scientist-engineers” who will lead a rapidly evolving industry. The institute’s Knowledge Centers serve as shared laboratories where trainees from diverse disciplines in science, engineering and medicine pursue projects under the mentorship of the center’s Directors, thereby gaining hands-on skills in high-throughput screening, medicinal chemistry, metabolomics, protein chemistry, and structural biology.
The Innovative Medicines Accelerator (IMA) emerged out of Stanford’s Long Range Vision and seeks to accelerate the translation of Stanford research discoveries into new medicines while expanding our knowledge of human biology. Part of the Drug and Vaccine Prototyping arm of the IMA, the Cell and Gene Therapies portfolio focuses on supporting novel therapeutic development in these research areas through annual seed grant opportunities and internal and external partnerships.
Our VPDoR Diversity Journey:
● We create a hub of innovation through the power of diversity of disciplines and people.
● We provide equitable access and opportunity to all members of the community in order to do their best work, regardless of race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
● We listen to and value all colleagues who bring diverse perspectives to the advancement and development of a respectful community.
● We promote a culture of belonging, equity, and safety.
● We embed these values in excellence of education, research, and operation.
POSITION SUMMARY:
Stanford University is seeking a highly motivated scientist to serve as the Research Scientist, Cell and Gene Therapies for the Stanford Innovative Medicines Accelerator (IMA), a partnership between Sarafan ChEM-H and Stanford Medicine. You will play a critical role in enabling projects at multiple stages of the translational pipeline, helping to create new prototype medicines. Your work will focus primarily on developing novel cell based functional assays, including the development of 3D and/or organoid models to characterize and screen gene therapy viral vectors. Candidates should have a strong scientific background, experience with the process of gene and cell therapy drug discovery and development, and excellent time management and organizational skills. You should be capable, interested in performing essential functions and activities involved in defined translational research projects, and able to independently conduct and analyze experiments.
In this position, you will be a member of the IMA scientific team supporting the Cell and Gene Therapies portfolio within the Drug and Vaccine Prototyping program. Reporting to the IMA Director of Cell and Gene Therapies, you will work closely with faculty, industry partners, and internal stakeholders to implement and troubleshoot key laboratory experiments critical to the acceleration of new medicines in the cell and gene therapies space. You will work with internal and external partners to realize the goals of this bold translational research program.
CORE DUTIES:● Support complex drug development programs related to cell and gene therapies; analyze data, monitor and oversee experimental processes, and design and develop prototypes, specialized equipment, and/or systems.
● Collaborate with scientists, engineers, and senior administrative officers to oversee complex non-routine analyses, select optimum solutions, and perform corrective modifications to equipment and system designs.
● Carry out all activities, including troubleshooting and resolving routine problems, independently.
● Collaborate with senior scientists to design and develop special purpose equipment and/or systems.
● Participate in the implementation of drug development work plans, and work toward project objectives in a highly collaborative environment.
● Serve as a resource in review of research capabilities and make recommendations.
● Establish, communicate, and enforce compliance with health and safety policies and procedures.
● Develop training manuals and safety guidelines, and train new instrumentation users, researchers, and/or technical staff.
MINIMUM REQUIREMENTS:
Education & Experience:
Bachelors’ degree in engineering, science, or related field, or five years of equivalent work experience or combination of education and relevant experience.
Knowledge, Skills and Abilities:
● Strong expertise in mammalian cell culture work, including establishing, optimizing and troubleshooting cell based functional assays.
● Extensive knowledge and hands-on expertise in transfection and viral transduction.
● Strong expertise in molecular biology including the design and execution of ddPCR, qPCR, RT-PCR assays.
● Demonstrated knowledge and skills of advanced scientific principles and practices. Extensive experience applying complex scientific principles and performing special technical services involving both development and performance.
● Ability to independently oversee and manage instrumentation or system installation.
● Ability to collaborate with senior engineering and scientific staff to design and develop special purpose equipment and/or systems.
● Experience overseeing the plan, design, and implementation of major scientific or engineering initiatives and ensuring project objectives are met.
● Demonstrated ability to evaluate research capabilities and make recommendations.
● Demonstrated ability to establish, communicate, and enforce compliance with health and safety policies and procedures.
● Experience overseeing a laboratory space or unit and supervising the work of technicians and other staff associated with the group.
● Demonstrated ability to effectively train a diverse work staff.
PREFERRED QUALIFICATIONS:
● Highly preferred: PhD. in Molecular Biology, Gene Therapy, Cell Biology or related fields with 4+ years academia and/or industry experience in gene therapy discovery research.
● Extensive knowledge in flow cytometry.
● Ability to prioritize own work and multi-task.
● Demonstrated ability to take initiative and ownership of research processes.
● Ability to routinely and independently exercise sound judgment in making decisions.
● Experience working independently and as part of a team.
● Ability to work with project management tools.
● Industry experience is highly preferred.
PHYSICAL REQUIREMENTS*:
● Frequently grasp lightly/fine manipulation, perform desk-based computer tasks, lift/carry/push/pull objects that weigh up to 10 pounds.
● Occasionally stand/walk, sit, twist/bend/stoop/squat, grasp forcefully.
● Rarely kneel/crawl, climb (ladders, scaffolds, or other), reach/work above shoulders, use a telephone, writing by hand, sort/file paperwork or parts, operate foot and/or hand controls, lift/carry/push/pull objects that weigh >40 pounds.
* – Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of the job.
WORKING CONDITIONS:
● May require working in close proximity to blood borne pathogens.
● May require work in an environment where animals are used for teaching and research.
● Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
● Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
● May require extended or unusual work hours based on research requirements and business needs.
WORK STANDARDS:
● Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
● Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.
● Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu.
For On-site or Hybrid positions:
The expected pay range for this position is $104,000 to $129,000 per annum.
Stanford University provides pay ranges representing its good faith estimate of what the university reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs.
At Stanford University, base pay represents only one aspect of the comprehensive rewards package. The Cardinal at Work website (https://cardinalatwork.stanford.edu/benefits-rewards) provides detailed information on Stanford’s extensive range of benefits and rewards offered to employees. Specifics about the rewards package for this position may be discussed during the hiring process.
Why Stanford is for You
Imagine a world without search engines or social platforms. Consider lives saved through first-ever organ transplants and research to cure illnesses. Stanford University has revolutionized the way we live and enrich the world. Supporting this mission is our diverse and dedicated 17,000 staff. We seek talent driven to impact the future of our legacy. Our culture and unique perks empower you with:
● Freedom to grow. We offer career development programs, tuition reimbursement, or audit a course. Join a TedTalk, film screening, or listen to a renowned author or global leader speak.
● A caring culture. We provide superb retirement plans, generous time-off, and family care resources.
● A healthier you. Climb our rock wall, or choose from hundreds of health or fitness classes at our world-class exercise facilities. We also provide excellent health care benefits.
● Discovery and fun. Stroll through historic sculptures, trails, and museums.
● Enviable resources. Enjoy free commuter programs, ridesharing incentives, discounts and more!
The job duties listed are typical examples of work performed by positions in this job classification and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks, and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned.
Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
Additional Information
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