The Kumar Lab, within the Division of Pediatric Pulmonary Medicine, is seeking a Life Science Research Professional to assist on a project studying the cellular and molecular mechanisms that control the development, maintenance, and repair of the pulmonary blood vessels of the mouse, with the long-term goal of understanding and treating pulmonary vascular disease. The Kumar laboratory’s long-term goals are to identify the cells, cell behaviors, and interactions that give rise to pulmonary vascular disease, delineate the molecular pathways that control them, and determine how they can be manipulated to prevent or reverse disease.
The selected candidate will employ cutting-edge genetic and single-cell approaches, including single-cell RNA-sequencing and spatial transcriptomics in mouse and human patient tissues, high-resolution deep imaging, in vivo lineage tracing, and pharmacologic manipulation in mice to discover how cell patterns, behaviors, interactions, and functions are altered in pulmonary disease.
The LSRP will perform experiments under the supervision of the PI. S/he may be expected to troubleshoot existing protocols and develop novel protocols and procedures. The LRSA will be responsible for managing the lab’s mouse colony. The position will also entail some lab support tasks such as ordering and maintaining lab supplies and equipment, maintaining lab records, and adhering to safety regulations.The candidate will be mentored by faculty and will be encouraged to contribute to publications, present work at meetings, participate in weekly lab meetings; and motivated candidates will have the opportunity to lead projects.
·Bachelor’s degree in biology or related discipline
·Lab experience, including experience with standard molecular biology techniques (PCR) and genetics. Experience with mouse colony maintenance, immunohistochemistry, in situ hybridization, confocal microscopy, and bioinformatics is a plus.
·Ability to work independently on multiple assigned tasks, to work well in a collaborative environment, to readily learn new techniques
·Strong communication, data recording, and organizational skills.
For more information about the lab:
·Plan experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
·Independently conduct experiments; maintain detailed records of experiments and outcomes.
·Apply the theories and methods of a life science discipline to interpret and analyze experimental results; offer suggestions for modifications to procedures and protocols in collaboration with senior researcher.
·Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
·Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
·Assist with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
·Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned
Stanford University provides pay ranges representing its good faith estimate of what the University reasonably expects to pay for a position. The pay offered to a selected candidate will be determined based on factors such as (but not limited to) the scope and responsibilities of the position, the qualifications of the selected candidate, departmental budget availability, internal equity, geographic location and external market pay for comparable jobs. The pay range for this position working in the California Bay area is between $53,000 to $76,000 based on commensurate experience and background.
Basic programming and computational skills
Experience with R
Basic understanding of biological principles
Strong communication skills
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor’s degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
·General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
·Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
·Ability to maintain detailed records of experiments and outcomes.
·General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
·Ability to work under deadlines with general guidance.
·Excellent organizational skills and demonstrated ability to accurately complete detailed work.
CERTIFICATIONS & LICENSES:
·Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
·Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
·Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
·Must have correctible vision to perform duties of the job.
·Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
·Ability to lift heavy objects weighing up to 50 pounds.
·Ability to work in a dusty, dirty, and odorous environment.
·Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
·May require working in close proximity to blood borne pathogens.
·Requires work in an environment where animals are used for teaching and research.
·Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
·Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
·May require extended or unusual work hours based on research requirements and business needs.