The Immunogenicity and Mechanistic Immunology group in the Biologics Research Center (BRC) in Cambridge focuses on understanding and exploiting the molecular and immunological mechanisms for the discovery, characterization and optimization of biotherapeutics and cell and gene therapies.
We are seeking a highly motivated and collaborative scientist to join our immunology team to profile our therapeutics modalities and their interactions with tumor cells and the immune system.
Your key responsibilities are, but not limited to:
• Develop and independently execute immunological, cellular and biochemical assays needed to assess and optimize CAR-T cells and immune cell engager functionality
• Conducting ex vivo cell-based assays using T cells and other primary cells from human peripheral blood and tissues to study functional interactions between CAR-T or immune cell engagers, tumor and immune cells
• Critically analyze and interpret data, able to prioritize experiments and design follow-up experiments
• Work collaboratively with team members of the Mechanistic Immunology groups and with other collaborators at BRC, Oncology and Discovery Science departments
• Regularly communicate and present results to lab head and project teams, prepare protocols and reports
• Open mindset, ability and eagerness to learn novel techniques or analysis tools based on project needs
• Maintain familiarity with scientific and technical literature pertinent to the projectsCommitment to Diversity & Inclusion:
We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:
Role Requirements
BSc or MSc in Life Science disciplines, preferably immunology or cell biology/biochemistry with at least 2 years research experience in human immunology, cell biology or biochemistry in industry or academia or recent Ph.D. graduate in immunology or cancer cell biology fields.
• Solid knowledge and interest in human immunology and cell biology/biochemistry.
• Experience with primary cell culture, human T cell or other immune cells including phenotyping and multicellular functional assays and protein biochemistry
• Demonstrated ability to develop new assays, critically analyze data, learn and combine new techniques and concepts quickly, design experiments and perform exploratory activities
• Scientific curiosity, initiative, commitment, flexibility and good organization and presentation skills
• Work independently and as a team member with open communication with the groups and collaborators
Desirable Requirements:
• Experience in virology or cell and gene therapy is a plus but not mandatory.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards
Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $92,800 and $139,200/year; however, while salary ranges are effective from 1/1/23 through 12/31/23, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network
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