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GlaxoSmithKline Hiring for Downstream Scientist – mRNA purification at Rockville, MD Full Time
Job Description
Site Name: USA – Maryland – Rockville, USA – Delaware – Dover , USA – Delaware – Wilmington, USA – Virginia – Arlington, Washington DC
Posted Date: Mar 1 2023
Posted Date: Mar 1 2023
We are delighted that we recently signed a contract to expand our space at Cambridge Park Drive (CPD Cambridge, MA) significantly. The expansion of the CPD facility is focused primarily on lab space and will bring together talent and expertise, especially to focus on cutting edge technologies. The lease for Rockville Vaccines site, where this role is currently being recruited, will expire by Q2 2026 and we have decided not to renew the lease. Consequently, this lab-based role may be relocated to Boston, Massachusetts in 2025.
//Field based worker, expected to be on-site//
The Nucleic Acid Vaccines Center of Excellence (NAV CoE), a team within the GSK Vaccine’s Technical Research and Development organization, has as a mission to develop the next generation mRNA vaccine platforms for rapid development of new vaccine candidates.
The NAV CoE is looking for a motivated scientist to join the downstream development team and drive development of new downstream processes for clinical & commercial manufacturing of mRNA. Located in Rockville, MD, the position will play a significant role in shaping current and next generation GSK’s leading mRNA vaccine platforms to accelerate addressing unmet medical needs, an exciting field having a direct impact into patients and global health. This role provides the opportunity to integrate a diverse group of top talented experts in vaccines’ industry, lead key activities and further grow and progress in your career.
Main core responsibilities
* Hands-on development of purification processes for mRNA manufacturing and tech transfer
* Development and implementation of innovative technologies for rapid downstream development
* Contribute to building next generation mRNA platform workflows and integration within the later-stage global platform
* Stay ahead with the latest quality and regulatory guidance to support project documentation and accelerated CMC submissions.
Why you?
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
* MS Degree in Biochemistry, Molecular Biology, Chemical Engineering, Biochemical Engineering, or a related scientific field.
* Two or more years of experience with different purification techniques such as chromatography and tangential flow filtration (TFF) and associated instrumentation such as AKTA chromatography systems and Unicorn software.
* Two or more years of experience in research and development in Biopharmaceutical industry or government laboratory setting is a must.
Preferred Qualifications:
If you have the following characteristics, it would be a plus:
* PhD in Biochemistry, Molecular Biology, Chemical Engineering, Biochemical Engineering, or a related scientific field.
* Experience with Quality by Design and demonstrated capability to develop downstream process for purification of biomolecules, specifically large size mRNA.
* Experience in Design of Experiments (DoE) & high-throughput process development (e.g. plates or robocolumns in Liquid Handling systems such TECAN)
* Experience and understanding of nucleic acid analytical technologies.
Why GSK?
We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.
In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
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